Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Interspecies Interactions
The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)
Image credit: Drs. Larry Gallagher and Joseph Mougous
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
News & Updates
The Department is seeking application for an Assistant Teaching Professor position, starting Fall 2025. Apply here: https://apply.interfolio.com/163023
Assistant Professor Tristan Jordan has been awarded 5 years of funding through the prestigious NIH DP2 New Innovator Award. Congratulations Dr. Jordan!
Congratulations to Dr. Alex Meeske on being named a 2024 Rita Allen Foundation Scholar for his work demistifying the genomic 'dark matter' of bacterial immune systems. Click here to learn more about the award the Rita Allen Foundation.
Professor Michael Lagunoff has been selected as Co-Director of the Seattle Molecular & Cell Biology PhD program, spanning research labs at UW, FHCC and beyond. Congratulations Dr. Lagunoff!
Upcoming Events
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Recent Publications
Blood advances
Feb, 2025
Cell host & microbe
Feb, 2025
bioRxiv : the preprint server for biology
Jan, 2025
bioRxiv : the preprint server for biology
Jan, 2025
Proceedings of the National Academy of Sciences of the United States of America
Jan, 2025
Journal of bacteriology
Jan, 2025
medRxiv : the preprint server for health sciences
Jan, 2025
bioRxiv : the preprint server for biology
Jan, 2025
Fast Facts
