Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
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Inflammatory Death of Mouse Macrophages
Mouse macrophages undergoing pyroptosis.
Courtesy of: Cookson Lab
News & Updates
E. Peter Greenberg, the inaugural Eugene and Martha Nester Professor of Microbiology at the University of Washington, joins Bonnie L. Bassler, Squibb Professor and chair of Molecular Biology at Princeton University, and Michael R. Silverman, emeritus investigator at The Agouron Institute and emeritus adjunct professor, Scripps Institution of Oceanography, in receiving the 2023 Canada Gairdner International Award. Each year, the Gairdner Foundation honors individuals who have made truly outstanding contributions in biomedicine or global health. The Gairdner Foundation press release can be found here.
The Department of Microbiology welcomes new Assistant Professor, Dr. Tristan Jordan, who joined the department in January, 2023.
Dr. Jordan indicates “Several things about the UW and UW Micro drove me to join. First and foremost, was the science. I loved the rigor and diversity of the science that was on-going in the Department of Microbiology and the UW as a whole. The collaborative atmosphere of the Department and biomedical science in Seattle, in general, was also a significant draw. It felt like a breath of fresh air to see and hear about all the collaborations that exists.”
Upcoming Events
Seminar
Orin Smith Auditorium/ Zoom
Speaker:
Dr. KC Huang
Fast Facts
