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  • listeria infecting cells

    Cell Biology of Bacterial Infection

    Listeria monocytogenes (green) interacting with macrophages (red/blue). 

    Credit: Michelle Reniere

  • southlakia epibionticum

    Interspecies Interactions

    The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)

    Image credit: Drs. Larry Gallagher and Joseph Mougous

  • Bacterial Self-Organization

    Bacterial Self-Organization

    Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).

    Credit: Jeffrey Carey and Matt Parsek

  • phage antagonize CRISPR

    Phage antagonize CRISPR-Cas Immunity

    Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).

    Credit: Alex Meeske

  • uropathogenic

    Emergence of Highly Pathogenic Clones of Escherichia coli

    Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.

    Courtesy: Sokurenko Lab

  • greenberg

    Quorum sensing in Vibrio fischeri

    Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.

    Courtesy: Greenberg Lab

  • Pseudomonas aeruginosa in co-culture

    Pseudomonas aeruginosa in co-culture

    Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).

    Courtesy of: Mougous Lab

  • envelope

    HIV-1 Envelope Evolution

    Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.

    Courtesy of: Mullins Lab

  • biofilm

    Pseudomonas aeruginosa

    Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.

    Courtesy of: Harwood Lab

  • yopm

    YopM Crystal Structure

    Crystal structure of the Yersinia virulence protein YopM

    Courtesy of: Cookson Lab

News & Updates


Kaitlin Hulce (Smith lab) has received two years of support from the NIH Ruth L. Kirschstein NRSA F32 fellowship program. Congratulations Kaitlin!

umbrella toxins

Professor Joseph Mougous and colleagues (including first author Qinqin Zhao) describe the structure and activity of a newly identified class of umbrella-shaped Streptomyces toxins in the April 17th issue of Nature. See the UW Newsroom highlight for more info.

Prof Fuller

Prof. Fuller has been selected to be recognized at the Center's 6th Latinx Faculty Recognition Event. This special event honors the scholarly achievements of Latinx faculty across the tri-campuses of the University of Washington for 2022-2024.


Sora Kim (Guo Lab) won 3 years of postdoctoral research support as part of this prestigious fellowship. Congrats Sora!

Upcoming Events

Dr. Jennifer Hyde
Orin Smith Auditorium
Dr. Jennifer Hyde

Recent Publications

The Journal of clinical investigation
Jun, 2024
Joy J, Gervassi AL, Chen L, Kirshenbaum B, Styrchak S, Ko D, McLaughlin S, Shao D, Kosmider E, Edlefsen PT, Maenza J, Collier AC, Mullins JI, Horton H, Frenkel LM, ...
Journal of the American Geriatrics Society
Jun, 2024
Ross SE, Severance JJ, Murphy SC, Yockey RA, Morkos J, Johnson S, Knebl JA
bioRxiv : the preprint server for biology
May, 2024
Dadonaite B, Ahn JJ, Ort JT, Yu J, Furey C, Dosey A, Hannon WW, Baker AV, Webby RJ, King NP, Liu Y, Hensley SE, Peacock TP, Moncla LH, Bloom JD, ...
bioRxiv : the preprint server for biology
May, 2024
Rubio AA, Baharani VA, Dadonaite B, Parada M, Abernathy ME, Wang Z, Lee YE, Eso MR, Phung J, Ramos I, Chen T, Nesr GE, Bloom JD, Bieniasz PD, Nussenzweig MC, Barnes CO, ...

Fast Facts

More than 175 undergraduate majors and 40 graduate students
Five National Academy of Sciences Members
Twelve American Academy of Microbiology Fellows
2023 publications