Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
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Inflammatory Death of Mouse Macrophages
Mouse macrophages undergoing pyroptosis.
Courtesy of: Cookson Lab
News & Updates
On 6/13/23, UW Medicine launched the Microbial Interactions & Microbiome Center to catalyze research in the Pacific Northwest focused on microbial communities. The new center, led by Dr. Joseph Mougous, the Lynn M. and Michael D. Garvey Endowed Chair in Gastroenterology, Professor of Microbiology and Investigator of the Howard Hughes Medical Institute at UW, will bring together scientists from diverse disciplines to study how microbes interact with each other and with their hosts, as well as the functional importance of microbiomes in the environment and in human health and disease.”
See the UW Newsroom Article.
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UW Medicine launches a new center to study microbiomes Today UW Medicine launched the Microbial Interactions & |
Dr. E. Pete Greenberg is being recognized with one of the most prestigious and inspirational international scientific awards, the 2023 Princess of Asturias Award for Technical and Scientific Research. The award is bestowed jointly with two other scientists, Bonnie Bassler and Jeffrey Gordon. Their Majesties King Felipe and Queen Letizia of Spain, accompanied by HRH Princess of Asturias Leonor, will preside over the ceremony of the Princess of Asturias Awards which will take place on Friday 20th October in the Spanish town of Oviedo.
E. Peter Greenberg, the inaugural Eugene and Martha Nester Professor of Microbiology at the University of Washington, joins Bonnie L. Bassler, Squibb Professor and chair of Molecular Biology at Princeton University, and Michael R. Silverman, emeritus investigator at The Agouron Institute and emeritus adjunct professor, Scripps Institution of Oceanography, in receiving the 2023 Canada Gairdner International Award. Each year, the Gairdner Foundation honors individuals who have made truly outstanding contributions in biomedicine or global health. The Gairdner Foundation press release can be found here.
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