Employment Opportunities with Microbiology, UW
Reniere Lab Postdoctoral Fellow
The Reniere Lab in the Department of Microbiology at the University of Washington School of Medicine in Seattle is hiring! We are looking for a postdoctoral fellow to join our team researching bacterial pathogenesis. Specifically, we are funded by the Cystic Fibrosis (CF) Foundation to investigate how Staphylococcus aureus survives in the unique nutritional environment of CF sputum in order to cause disease in the immunocompromised host. This project will integrate clinical isolates, patient specimens, and clinical data with ex vivo and in vitro analysis. The ideal candidate will be well-organized and able to coordinate this exciting collaboration with clinicians and core facilities at UW Medicine and Seattle Children’s Hospital. The anticipated start date is flexible.
Competitive candidates will have a Ph.D. in microbiology or a related field and have experience with bacterial genetics. A background in S. aureus genetics specifically is a plus. To apply, please email Dr. Reniere (reniere@uw.edu) a cover letter stating why you are interested in this position, your recent CV, and the names of at least three references, with the subject line ‘Postdoctoral Application’. For more information about the lab, visit renierelab.com
A postdoctoral position is open in the Harwood laboratory at the University of Washington in Seattle to study the role of the stringent response in bacterial longevity. It is well known that bacteria can survive in a growth-arrested state for long periods of time, on the order of months or even years, without forming dormant structures like spores or cysts. How is such longevity possible? What is the molecular basis of such longevity? The physiology of fast-growing bacteria is well characterized, but relatively little is understood about how cells maintain life under non-growing conditions. We have been studying this crucial phase of the bacterial life cycle using the alpha-proteobacterium Rhodopseudomonas palustris as a model. This microbe stays fully viable for months when in growth arrest. We know that that active translation and optimized ribosomes are critical for its longevity, as is the stringent response mediated by guanosine polyphosphate [(p)ppGpp]. We now plan to study specific molecular mechanisms responsible for extreme longevity.Applicants must have first author publications and a background in microbial physiology, biochemistry and molecular genetics, as well as a high level of motivation. Applicants should email their CV and the names and e-mail addresses of two references to Carrie Harwood at csh5@uw.edu.
Most relevant publications:
Yin L, Ma H, Nakayasu ES, Payne SH, Morris DR, Harwood CS. 2019. Bacterial longevity requires protein synthesis and a stringent response. mBio, Oct 15;10(5). pii: e02189-19. doi: 10.1128/mBio.02189-19.Pechter KB, Yin L, Oda Y, Gallagher L, Yang Y, Manoil C, Harwood CS. 2017. Molecular basis of bacterial longevity. mBio. doi:10.1128/mBio.01726-17
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