Interspecies Interactions
The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)
Image credit: Drs. Larry Gallagher and Joseph Mougous
UW Microbiology Home
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Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
News & Updates
Congratulations to the 2025 Department of Microbiology undergraduate awardees!
Click this link to learn more about the awards and awardees.
Prof. Matt Parsek was named a 2024 American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow honors members whose efforts on behalf of the advancement of science or its applications in service to society have distinguished them among their peers and colleagues. Congratulations Dr. Parsek!
Dr. Parsek was also featured on The UW Medicine Huddle and the UW NEWS.
Assistant Professor Tristan Jordan has been awarded 5 years of funding through the prestigious NIH DP2 New Innovator Award. Congratulations Dr. Jordan!
Congratulations to Dr. Alex Meeske on being named a 2024 Rita Allen Foundation Scholar for his work demistifying the genomic 'dark matter' of bacterial immune systems. Click here to learn more about the award the Rita Allen Foundation.
Recent Publications
Nature chemical biology
Jun, 2025
Annals of the American Thoracic Society
Jun, 2025
The Journal of pharmacology and experimental therapeutics
Jun, 2025
Nucleic acids research
Jun, 2025
Journal of virology
Jun, 2025
Cell genomics
Jun, 2025
Molecular biology and evolution
Jun, 2025
Fast Facts
