Jason G. Smith
Jason G. Smith
Reflecting on STEM Instructor Identity, Positionality and Privilege, UW PR2ISM, July 29, 2020
Understanding URM Undergraduate STEM Student Experiences, UW PR2ISM, July 31, 2020
Developing an Equitable STEM Curriculum, UW PR2ISM, August 5, 2020
Building Healthy Workplaces - Biomedical Research Programs, Empowering Prevention & Inclusive Communities (EPIC), September 9, 2020
Reimagining Mentoring, HHMI Gilliam, Dept of Chemistry, PR2ISM, ISCRM, April 29, 2022
Identity Privilege, Intersectionality, Office of Healthcare Equity (OHCE), November 14, 2022
History of Race and Racism in Science and Medicine, OHCE, November 14, 2022
Building Healthy Workplaces: Community Prevention Strategies & Bystander Skills, EPIC, January 11, 2023
T32 Mentors Retreat led by Dr. Monica Gandhi (UCSF), August 1, 2023
Mentoring for Lunch, UW Allies, November 18, 2024
The Smith lab is primarily focused on understanding the role of defensins in viral pathogenesis and evolution. Defensins are a class of antimicrobial peptides with broad antibacterial, antiviral, and antifungal activity. Their effects on viral infection, immunity, pathogenesis, and evolution, particularly for nonenveloped viruses, are incompletely understood. Using a variety of approaches from virology, cell biology, biochemistry, structural biology, and genetics, our work is focused on understanding the interaction of defensins with non-enveloped viruses in molecular detail to determine general principals of defensin-mediated neutralization of viral infection. We are also interested in using animal models of enteric viral diseases to understand the role of defensins in antiviral immunity in vivo. Finally, we use 3D intestinal enteroid culture methodology to examine the interaction of viruses and bacteria with host cells and to study the cell biology of epithelial cell types that were previously unculturable.
Farewell to Jess in 2024
Award Winner, Hannah Kim, in 2024
Lab Outing in 2023
Windy Day in 2022
Pumpkin Carving in 2022
2021 Baseball
Wine Tasting in 2019
2019 Baseball
2018 Baseball
2017 Baseball
2014 Baseball