Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Interspecies Interactions
The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)
Image credit: Drs. Larry Gallagher and Joseph Mougous
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
News & Updates
Assistant Professor Tristan Jordan has been awarded 5 years of funding through the prestigious NIH DP2 New Innovator Award. Congratulations Dr. Jordan!
Congratulations to Dr. Alex Meeske on being named a 2024 Rita Allen Foundation Scholar for his work demistifying the genomic 'dark matter' of bacterial immune systems. Click here to learn more about the award the Rita Allen Foundation.
Professor Michael Lagunoff has been selected as Co-Director of the Seattle Molecular & Cell Biology PhD program, spanning research labs at UW, FHCC and beyond. Congratulations Dr. Lagunoff!
The Department mourns the loss of Jim Staley, who served on the faculty from 1982 until his retirement in 2008. During that time, he wrote and published Microbial Life and Microbiology Dynamics & Diversity, and served as the Founding Director of the Astrobiology Program from 1998-2005. He became a Bergey’s Manual Trustee in 1976, Chair of Bergey’s Trust in 2000, and retired from the Trust at the mandatory age of 70 in 2008, the same year he received the Bergey Medal. During his chairmanship, he initiated and served as President of Bergey's International Society for Microbial Systematics (BISMiS) from 2009 - May 2011. Jim was a member of the American Society for Microbiology (ASM) for more than 50 years and received the US Federation of
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Recent Publications
PloS one
2024
Communications biology
Oct, 2024
bioRxiv : the preprint server for biology
Oct, 2024
Gerontology & geriatrics education
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Bone marrow transplantation
Oct, 2024
Research square
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bioRxiv : the preprint server for biology
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