Cell Biology of Bacterial Infection
Listeria monocytogenes (green) interacting with macrophages (red/blue).
Credit: Michelle Reniere
UW Microbiology Home
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Interspecies Interactions
The tiny obligate parasitic bacterium Southlakia epibionticum(yellow) cultured on its host bacterium, Actinomyces israelii (blue)
Image credit: Drs. Larry Gallagher and Joseph Mougous
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Bacterial Self-Organization
Pseudomonas aeruginosa cells that engage (magenta) or don’t (green) in collective behavior spontaneously self organize in cellular aggregates (3D image acquired by confocal laser scanning microscopy).
Credit: Jeffrey Carey and Matt Parsek
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Phage antagonize CRISPR-Cas Immunity
Cryo-EM structure of a phage-encoded anti-CRISPR protein (blue) in complex with the RNA-targeting CRISPR effector Cas13 (gray) and its guide RNA (red).
Credit: Alex Meeske
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Emergence of Highly Pathogenic Clones of Escherichia coli
Genetic typing of uropathogeic E. coli reveals strong association of some clones with high sensitivity or extreme resistance to multiple antibiotics.
Courtesy: Sokurenko Lab
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Quorum sensing in Vibrio fischeri
Lux genes coding for light production are activated by quorum sensing at high cell density. The light produced by the bacteria exposed the film for the image.
Courtesy: Greenberg Lab
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Pseudomonas aeruginosa in co-culture
Structural component of bacterial targeting type VI secretion system P. aeruginosa (green) assembled in presence of competitor organism (red).
Courtesy of: Mougous Lab
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HIV-1 Envelope Evolution
Reconstructed phylogenetic network of HIV-1 envelope sequences (C2-V5) from subtype B.
Courtesy of: Mullins Lab
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Pseudomonas aeruginosa
Colonies of Pseudomonas aeruginosa expressing different amounts of exopolysaccharides.
Courtesy of: Harwood Lab
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YopM Crystal Structure
Crystal structure of the Yersinia virulence protein YopM
Courtesy of: Cookson Lab
News & Updates
Prof. Matt Parsek was named a 2024 American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow honors members whose efforts on behalf of the advancement of science or its applications in service to society have distinguished them among their peers and colleagues. Congratulations Dr. Parsek!
The Department is seeking application for an Assistant Teaching Professor position, starting Fall 2025. Apply here: https://apply.interfolio.com/163023
Assistant Professor Tristan Jordan has been awarded 5 years of funding through the prestigious NIH DP2 New Innovator Award. Congratulations Dr. Jordan!
Congratulations to Dr. Alex Meeske on being named a 2024 Rita Allen Foundation Scholar for his work demistifying the genomic 'dark matter' of bacterial immune systems. Click here to learn more about the award the Rita Allen Foundation.
Upcoming Events
Seminars
Orin Smith Auditorium
Speaker:
Dr. Bob Ernst
Recent Publications
bioRxiv : the preprint server for biology
Mar, 2025
bioRxiv : the preprint server for biology
Mar, 2025
Cell genomics
Mar, 2025
Journal of virology
Mar, 2025
American journal of respiratory and critical care medicine
Mar, 2025
Malaria journal
Mar, 2025
Irish journal of medical science
Mar, 2025
Fast Facts
