Keith R. Jerome

Contact Information

Email:

kjerome@uw.edu

Phone:

206 667-6793

Office:

Head, Virology Division, Laboratory Medicine

Mail Box:

358080

Keith R. Jerome

Adjunct Professor

Microbiology

Professor

Laboratory Medicine

Current Research:

Dr. Keith R. Jerome holds a B.S. in Chemistry from Georgetown College, and M.D. and Ph.D. degrees from Duke University, where his thesis focused on T cell antigens expressed by breast tumors. He did residency and fellowship training at the University of Washington. Dr. Jerome's research focuses on chronic and latent viruses, their immune evasion mechanisms, and potential curative therapeutic approaches to these infections. His most recent work involves the use of DNA editing enzymes such as homing endonucleases and zinc finger nucleases to specifically target latent viral DNA for cleavage and inactivation. This approach may allow precise elimination of functional viral DNA from infected cell reservoirs, offering the prospect of cure for HIV, hepatitis B, herpes simplex, and human papillomavirus infections.

Recent Publications from PubMed

Large, stable, contemporary interspecies recombination events in circulating human herpes simplex viruses.
Casto AM, Roychoudhury P, Xie H, Selke S, Perchetti GA, Wofford H, Huang ML, Verjans GMGM, Gottlieb GS, Wald A, Jerome KR, Koelle DM, Johnston C, Greninger AL
The Journal of infectious diseases. 2019 Apr; :
Evaluating addition of self-collected throat swabs to nasal swabs for respiratory virus detection.
Fisher CE, Boeckh M, Jerome KR, Englund J, Kuypers J
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 2019 Jun; 115 : 43-46
Hybrid nanocarriers incorporating mechanistically distinct drugs for lymphatic CD4 T cell activation and HIV-1 latency reversal.
Cao S, Slack SD, Levy CN, Hughes SM, Jiang Y, Yogodzinski C, Roychoudhury P, Jerome KR, Schiffer JT, Hladik F, Woodrow KA
Science advances. 2019 Mar; 5 3: eaav6322
Human Rhinovirus Infections in Hematopoietic Cell Transplant Recipients: Risk Score for Progression to Lower Respiratory Tract Infection.
Waghmare A, Xie H, Kuypers J, Sorror ML, Jerome KR, Englund JA, Boeckh M, Leisenring WM
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2019 May; 25 5: 1011-1021
RNA Sequencing of the Human Herpesvirus 6B Transcriptome To Identify Targets for Clinical Assays Distinguishing between Latent and Active Infections.
Hill JA, Ikoma M, Zerr DM, Basom RS, Peddu V, Huang ML, Hall Sedlak R, Jerome KR, Boeckh M, Barcy S
Journal of virology. 2019 Feb; 93 3:

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Profile Last Updated: November 27, 2017

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Contact Information

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Keith R. Jerome

Current Research:

Recent Publications from PubMed

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