Keith R. Jerome

Contact Information

Email:

kjerome@uw.edu

Phone:

206 667-6793

Office:

Head, Virology Division, Laboratory Medicine

Mail Box:

358080

Keith R. Jerome

Adjunct Professor

Microbiology

Professor

Laboratory Medicine

Current Research:

Dr. Keith R. Jerome holds a B.S. in Chemistry from Georgetown College, and M.D. and Ph.D. degrees from Duke University, where his thesis focused on T cell antigens expressed by breast tumors. He did residency and fellowship training at the University of Washington. Dr. Jerome's research focuses on chronic and latent viruses, their immune evasion mechanisms, and potential curative therapeutic approaches to these infections. His most recent work involves the use of DNA editing enzymes such as homing endonucleases and zinc finger nucleases to specifically target latent viral DNA for cleavage and inactivation. This approach may allow precise elimination of functional viral DNA from infected cell reservoirs, offering the prospect of cure for HIV, hepatitis B, herpes simplex, and human papillomavirus infections.

Recent Publications from PubMed

Antibiotic Exposure Prior to Respiratory Viral Infection is Associated with Progression to Lower Respiratory Tract Disease in Allogeneic Hematopoietic Cell Transplant Recipients.
Ogimi C, Krantz EM, Golob JL, Waghmare A, Liu C, Leisenring WM, Woodard CR, Marquis S, Kuypers JM, Jerome KR, Pergam SA, Fredricks DN, Sorror ML, Englund JA, Boeckh M
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2018 May; :
Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.
Peterson CW, Wang J, Deleage C, Reddy S, Kaur J, Polacino P, Reik A, Huang ML, Jerome KR, Hu SL, Holmes MC, Estes JD, Kiem HP
PLoS pathogens. 2018 Apr; 14 4: e1006956
Alveolar levels of immuno-inflammatory mediators in diffuse alveolar hemorrhage after allogeneic transplant.
Vande Vusse LK, Wurfel MM, Madtes DM, Schoch HG, Harju-Baker S, Hill JA, Jerome KR, Boeckh M, Watkins TR
Bone marrow transplantation. 2018 Apr; :
Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6.
Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang ML, Cook L, Depledge DP, Zerr DM, Koelle DM, Gantt S, Yoshikawa T, Caserta M, Hill JA, Jerome KR
BMC genomics. 2018 03; 19 1: 204
CRISPR/Cas9 and Genome Editing for Viral Disease-Is Resistance Futile?
De Silva Feelixge HS, Stone D, Roychoudhury P, Aubert M, Jerome KR
ACS infectious diseases. 2018 Mar; :

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Profile Last Updated: November 27, 2017

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Contact Information

Email:

Phone:

Office:

Mail Box:

Keith R. Jerome

Current Research:

Recent Publications from PubMed

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