Recent Publications from PubMed

• Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral sequence divergence.
  Hilton SK, Bloom JD
  Virus evolution. 2018 Jul; 4 2: vey033
• Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones.
  Phillips AM, Ponomarenko AI, Chen K, Ashenberg O, Miao J, McHugh SM, Butty VL, Whittaker CA, Moore CL, Bloom JD, Lin YS, Shoulders MD
  PLoS biology. 2018 Sep; 16 9: e3000008
• Estimating the frequency of multiplets in single-cell RNA sequencing from cell-mixing experiments.
  Bloom JD
  PeerJ. 2018 ; 6 : e5578
• Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin.
  Phillips AM, Doud MB, Gonzalez LO, Butty VL, Lin YS, Bloom JD, Shoulders MD
  eLife. 2018 09; 7 :
• Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants.
  Lee JM, Huddleston J, Doud MB, Hooper KA, Wu NC, Bedford T, Bloom JD
  Proceedings of the National Academy of Sciences of the United States of America. 2018 08; 115 35: E8276-E8285